QFullSampleSize should be bigger than QFullThreshold. LUN queue depth throttling algorithm will not function as expected.
This event is from a subset that specifically concerns SCSI device issues.
There is an issue with the configuration or availability of this attached SCSI device.
Set the QFullSampleSize and QFullThreshold disk configuration values in ESX correctly.
See the event description for more detailed information specific to this event. Review the VMware online document vSphere Troubleshooting Guide for more assistance.
Refer to the VMware Online Documentation for more information on vCenter event messages and possible solutions.