You must add to the backup infrastructure VMware vSphere servers that you plan to use as source and target for backup, replication and other activities.
You can add vCenter Servers and ESXi hosts. If an ESXi host is managed by a vCenter Server, it is recommended that you add the vCenter Server, not a standalone ESXi host. If you move VMs between ESXi hosts managed by the vCenter Server, you will not have to re-configure jobs in Veeam Backup & Replication. Veeam Backup & Replication will automatically locate migrated VMs and continue processing them as usual.
To add a VMware vSphere server, use the New VMware Server wizard.